999 Cold and Flu Granules and Amoxicillin can be taken at the same time when colds are accompanied by bacterial infections, but it is not recommended to take at the same time for simple colds. 1. Can be taken at the same time: cold Ling particles are mainly used for colds caused by fever, nasal congestion and runny nose, headache, sore throat, cough and other uncomfortable symptoms of relief, when the patient combined with bacterial infection based on the physician’s guidance can be combined with antibiotics, such as amoxicillin capsules to take together. 2. Can not be taken at the same time: viral infections caused by colds, cold particles can relieve the discomfort caused by the symptoms; but amoxicillin is an antibiotic, the virus does not have any therapeutic effect, but also increase the risk of adverse drug reactions, but also cause the abuse of antibiotics. There are many medications available for the treatment of colds and flu, and it is recommended that you choose the appropriate medication for your individual situation under the guidance of your physician and pharmacist.