The most common side effects of general anesthesia are nausea, vomiting, temporary urinary discomfort, muscle pain, or slight damage to the tongue or lips. Babies are unable to verbalize the discomfort, so it may manifest as irritability and crying. When you see your baby behaving this way, it is important to further care and understand the root cause of the discomfort, as well as to communicate more with the surgeon, who will perform post-surgical treatment to alleviate the baby’s discomfort. According to the latest literature, general anesthesia in children under 3 years of age may cause neurodevelopmental delays in the brain. Parents should weigh the benefits of surgery against the pros and cons of anesthesia and the effects on their baby before deciding on the timing of surgery. If the surgery is congenital or orthopedic, parents are advised to go for the surgery as early as possible after discovery to avoid functional or psychological effects when the child grows up.