Infants and young children have poor defenses and immature lung development, so they have the highest incidence within 2 years of age, most often following upper respiratory infections and acute infectious diseases, and most often in winter and spring. Chronic cough, sputum and wheezing in winter and spring have an acute or delayed onset, and most of them are preceded by a mild upper respiratory tract infection. However, the cause of onset is determined by the specific clinical presentation. In addition to a detailed medical history and symptoms, what other tests are needed for chronic cough, sputum and wheezing in winter and spring? Routine blood test: Routine blood test is the most general and basic blood test. Blood consists of two major parts: fluid and tangible cells, and routine blood tests are performed on the cellular part of the blood. Sputum bacterial culture: When bacterial infection occurs in the human lungs or bronchi, the amount of sputum increases significantly. Sputum bacterial culture, which isolates pathogenic bacteria, helps in the diagnosis and treatment of infectious diseases of the lower respiratory tract. Electrocardiogram: It is a technique that uses an electrocardiogram machine to record from the body surface a graphical representation of the changes in electrical activity produced by the heart during each cardiac cycle. ECG is the best way to measure and diagnose abnormal heart rhythms. It is used to diagnose abnormal heart rhythms in cases of damaged cardiac conduction tissue and altered heart rhythms due to electrolyte imbalance. There is no significant therapeutic effect on antibacterial drugs, and their abuse should be avoided in the treatment of patients with acute bronchitis. However, if a patient presents with fever, purulent sputum and severe cough, this is an indication for the application of antimicrobial drugs. The application of antibacterial drugs for the treatment of patients with acute bronchitis can be applied against Chlamydia pneumoniae and Mycoplasma pneumoniae, such as erythromycin, but also clarithromycin or azithromycin. During influenza epidemics, anti-influenza treatment measures should be applied if there are manifestations of acute bronchitis.