Smallpox vaccine is not the same as chickenpox vaccine. Smallpox vaccine is mainly used to prevent a virulent infectious disease caused by smallpox virus, which is a kind of DNA virus with strong reproduction ability, and can spread throughout the body through blood circulation and cause viremia. Smallpox vaccine is mainly made by processing cowpox virus, which can stimulate the human immune system to produce corresponding antibodies, and can effectively prevent smallpox virus infection. Chickenpox vaccine is mainly used for an acute infectious disease caused by herpes zoster virus infection, which can be spread by airborne droplets or patient’s blister fluid and objects with blister fluid, and may initially lead to the appearance of red spots and pimples, which will later turn into fluid-filled herpes. Chickenpox vaccination is recommended for adults and young people who have never had chickenpox. Smallpox vaccination is also not necessary as the smallpox virus has been completely controlled and eradicated and the human body is not susceptible to smallpox virus. The vaccination should be administered at a hospital under the supervision of a doctor.