Gastric nodule usually refers to gastric nodular gastritis, which is caused by abnormal proliferation of gastric mucosa and can manifest as indigestion and bloating, etc. It can be treated by medication and surgery. The cause of gastric nodules, i.e., nodular gastritis, is unclear and may be related to Helicobacter pylori infection. Most of them are benign and only a few are malignant. Nodular gastritis may not have specific manifestations, but may also manifest as indigestion, abdominal distension, abdominal pain, etc. It is recommended that after the detection of gastric nodules, further improve the relevant examinations to clarify the nature of the nodules, and then symptomatic treatment. The main treatments for gastric nodules include medication and surgery. Drug treatment is to take gastric mucous membrane protection drugs, such as colloidal bismuth pectin capsules, under the guidance of doctors for treatment. If there is Helicobacter pylori infection, eradication treatment should be carried out by the quadruple method i.e. one proton pump inhibitor such as omeprazole + one bismuth such as colloidal bismuth + two antibiotics such as amoxicillin and clarithromycin. In more severe cases, gastroscopic resection of the nodule is recommended and the need for further treatment will be determined based on the pathologic findings. In conclusion, gastric nodule is the abbreviation of nodular gastritis, belongs to the gastritis caused by abnormal proliferation of gastric mucosa caused by a class of problems, can appear indigestion and other symptoms, it is recommended to further improve the examination, under the guidance of the doctor to take medication, if the nodule range is extensive, it is recommended that surgical treatment.