Systemic osteoarthritis refers to the inflammation of multiple bone joints throughout the body, which may cause severe pain in the bone joints, motor dysfunction, obstruction of normal joint movement and other discomforts. 1. Causing severe pain: Systemic osteoarthritis may compress the neighboring nerve roots, causing local pain and stiffness. If osteoarthritis compresses the sciatic nerve, then it will cause severe pain, such as numbness, burning pain, scurrying pain and so on. 2. Movement dysfunction: generalized osteoarthritis will cause joint pain and swelling, and even lead to osteophytes, which will limit joint movement and the body’s movement function will be impaired. 3. Obstruction of normal joint activities: generalized osteoarthritis usually occurs in joints with more activities, such as finger joints, knee joints, hip joints and so on. Osteoarthritis will lead to narrowing of the joint space, aging of the joints, and damage to the cartilage in the joints, thus hindering the normal movement of the joints. 4. Induce other complications: generalized osteoarthritis can lead to joint deformation, scoliosis, etc. It may also affect the patient’s heart and intestinal function, which may lead to heart disease and gastrointestinal disease. Generalized osteoarthritis may also cause bone spurs, muscle spasms and contractions, etc. It is recommended that patients consult a doctor in time to clarify the cause of the disease and follow the doctor’s instructions for standardized treatment.