Rectal drug delivery in women is mainly delivered into the intestinal canal through plugging deep into the anus, and the drug is absorbed into the bloodstream through the absorption of the intestinal mucosa, so as to achieve the therapeutic purpose. The patient’s body position is recommended to take the supine position, which is more conducive to smooth drug delivery. Before administering the medication, wash your hands and follow the instructions for the use of the medication to perform the correct operation. The more pointed end of the medication is inserted into the anus and the medication is pushed into the anus about two knuckles with a plastic gloved finger. The medication should be administered as close to bedtime as possible at night, and the integrity of the medication package should be ensured so that the medication can be fully absorbed during nighttime sleep by contact with the intestinal mucosa. Common medicines for rectal administration include metronidazole suppositories and tinidazole suppositories, which are absorbed through the rectal mucosa and can be helpful when the patient has localized inflammation, fever, pain, and poor circulation. On the basis of medication, patients should also pay attention to dietary control, the development of a good daily lifestyle, and if discomfort occurs, please consult a doctor promptly.