There is no exact data on the survival of pleomorphic lung cancer invading the pleura. Survival of patients with pleomorphic lung cancer invading the pleura is affected by many clinical factors, such as the patient’s physical status score and the sensitivity of anti-tumor treatment, etc. Generally speaking, the worse the physical strength and the less sensitive to the treatment, the shorter the survival period. Moreover, pleomorphic lung cancer is a rare type in clinic, so the clinical data about this type of lung cancer is relatively small. Polymorphic lung cancer is a rare type of non-small cell lung cancer, the malignancy of this type of lung cancer is similar to sarcomatoid carcinoma, so the disease develops rapidly, and the overall prognosis is relatively poor. Once pleural invasion occurs in polymorphic lung cancer, it indicates that the patient’s stage is late, which further shortens the patient’s survival period.