Low mood, irritability, feeling depressed and inexplicable crying may be due to the patient’s recent experience of some human affairs but no one to talk to, or due to the pressure or aggression deposited in the heart by work, life, study, family, disease and other aspects of the inability to vent the mood swings. If the symptoms are not long-term, but appear suddenly recently, we suggest that patients talk to their relatives or friends, or listen to music, sing, travel, write diary, etc. to relieve and vent their emotions. If the mood is low for a long time and cannot be relieved by oneself, it is considered that depression may be present and it is recommended to go to the psychology department of the hospital for consultation and treatment in a timely manner. Doctors will make preliminary judgments by observing the patient’s consciousness, attention, self-awareness, mood and other aspects, and standardized patient self-assessment scales and clinical other assessment scales are often used clinically as an important basis for screening and assessing the severity of depression. After diagnosis, patients need to take fluoxetine, escitalopram, griseofulvin, mirtazapine, bupropion and other medications regularly as prescribed by the doctor, and they also need to receive professional psychotherapy in order to get better treatment results. However, the patient’s own factors are more important. Patients need to build up self-confidence in life, affirm their own value, and not create too much pressure for themselves. Family members should also closely observe the patient’s actions in daily life, whether there are behaviors that endanger physical health or even life, and promptly stop, persuade, comfort and encourage, and urge the patient to take medication and receive systematic treatment on time and in accordance with the dosage to promote early recovery.