Purines exist in the body mainly in the form of purine nucleotides, which are involved in energy supply, metabolic regulation and the composition of coenzymes in the body. There are two sources of purines: one is metabolism in the body, where nucleic acids are in a constant process of decomposition and synthesis, and their decomposition produces large amounts of purines; the other is ingestion from food (mainly meat and seafood), where nucleic acids can be hydrolyzed into purines, pyrimidines, five-carbon sugars and phosphoric acid by the action of enzymes in the body. There are also two routes for purines: one is synthesis of nucleic acids with other substances by the action of enzymes; the other is catabolism, the main product of which is uric acid. The increase of purine sources and the decrease of purine routes will lead to an increase of purine. In the human body, the increase of purine will lead to the increase of decomposition, which will lead to the increase of uric acid and produce hyperuricemia, and the high uric acid in human body will cause gout. Uric acid stones will be deposited everywhere in the body, leading to arthritis, urinary stones and kidney disease. In order to prevent the increase of purine and the formation of gout, you can usually limit the intake of high purine food, fat and protein, eat more alkaline food, drink more tea and water, etc., and consult the hospital promptly if you have disease related manifestations.