During menstruation, there is no such thing as the fastest way to relieve pain. If pain occurs, you can take medication such as ibuprofen to relieve pain, in addition, you can also improve your lifestyle and other methods to relieve pain. 1. Medication: medication is the fastest way to treat menstrual cramps. When the cramps are more severe, you can take non-steroidal anti-inflammatory drugs such as ibuprofen to relieve the pain. 2. Improve lifestyle: Mild discomfort during menstruation is a physiological reaction, eliminating tension and worry can relieve pain. Adequate rest and sleep, regular and moderate exercise, and quitting smoking are all helpful in relieving pain. If the pain is intolerable, medication can be used. Women who experience more severe pain during menstruation are advised to seek prompt medical attention for reasonable treatment and avoid unauthorized use of medication.