Moles are benign swellings formed by mole cells, and almost everyone from infants to the elderly has them, and they gradually increase with age. However, moles and moles are not the same, some are flat, some are raised, some are dark, some are light, some are born and some appear only when they grow up, so the question arises, what kind of moles are safe and what kind of moles can be malignant? Can moles be taken or not? What method should be used to take it? I believe everyone has had similar questions in their mind. The following is a brief introduction to the most concerned issues: 1. Are moles that are safe since birth and moles that appear only after growing up unsafe? There are three kinds of moles: junctional moles, mixed moles and intradermal moles. Among them, junctional nevi are often present at birth or occur soon after birth, and can exist in all parts of the body, especially in the friction areas such as palmoplantar and perineum, and are the most prone to malignant changes. Of course, the other two types of moles are not absolutely safe either. Therefore, the safety of a mole cannot be judged by whether it was born or appeared later in life, and the ones born are not always the best. 2. Are flat moles safe and raised moles unsafe? The junctional nevus mentioned in the first question is usually flat or only slightly higher than the skin surface, while intradermal nevus is a hemispherical raised papule or nodule, but in fact, the chance of malignant transformation of junctional nevus is higher than that of intradermal nevus. Therefore, whether it is flat or not is not a criterion to judge the safety of moles. 3. Which is safer, a hairy mole or a hairless mole? There is also a saying circulating in academic circles: “A mole with long hair is not malignant!” Indeed, we have observed clinically that moles with malignant changes are often hairless, but there are also moles with long hair that have malignant changes. So, it is not absolute. 4. Is it bad to have dark colored moles and safe to have light colored moles? The color is not the most important, but the best is the uniform color. 5. Folklore says that moles on the jaw, forehead and nose are good, but moles on the eyelids and around the orbit are not good? Moles that grow on friction parts such as the palms of hands, feet and vulva have a high chance of malignant change because they are often stimulated by friction, especially because the most common parts of malignant melanoma in Chinese people are the palms of hands and feet, so moles in these parts need to be alert. If the director had arranged the mole of Mr. Sun Honglei as Mr. Xiangshan on the bottom of the foot instead of the back of the foot, it would have been more credible. However, there is no significant difference in the chance of malignancy of moles in different parts of the face, and the folklore that moles around the eyes are bad belongs to the category of facial physiognomy, which is not explained in this article. 6. These are not standards, so how can we judge whether a mole is safe or not? Remember the “three big developments”: asymmetry, irregularity, unevenness (color), large (diameter greater than 6mm), and development (increase in volume, deepening color, bleeding, breaking, itching, pain, etc.). According to the initials of the above 5 characteristics, they can also be simply remembered as ABCDE: Asymmetry, Border, Color, Diameter, Evolving. 7. Which moles can be taken and which moles cannot be taken? Moles with malignant tendency must be taken. Other moles can be taken as long as you want. 8. What is the best way to remove moles? Freezing? Laser? Or surgery? The principle of mole removal is: either you don’t take it or you do it completely! Therefore, surgical removal is preferred. However, many patients have many small facial moles, most of which are relatively safe, so freezing and laser are also options. Compared with surgical excision, freezing and laser are cheaper, relatively easy and fast to operate, and generally do not leave a scar. However, the disadvantage is that they are easy to recur. For recurring moles, repeated laser and freezing treatments are not recommended to avoid stimulating the malignant change of mole cells. In addition, these two methods also have the possibility of leaving scars and pigmentation. 9.Which moles must be removed by surgery? Will scars remain after surgical removal? Moles that are larger (2mm or more), rubbing areas, or have a tendency to become malignant must be completely removed by surgery. After surgery, a linear scar will be left behind, but with precise cosmetic suturing and topical scar removal medication after surgery, the scar can gradually fade to insignificant.