For the treatment of diabetic nephropathy, good glycemic control is emphasized first. At the same time, patients should be repeatedly educated about diabetes, such as: 1. Strictly control blood pressure, try to keep it below 130/80mmHg; 2. Strictly control the protein content in the diet, 0.6-0.8g/kg/day, and choose high-quality protein such as fish; 3. Strictly control blood sugar to slow down the process of developing microalbuminuria to clinical proteinuria; 4. Avoid taking drugs that are damaging to the kidney Avoid taking drugs that are damaging to the kidneys; 5. Exercise appropriately and maintain ideal body weight; 6. Prohibit smoking. In the early stage of the disease, only the increase of microalbuminuria is the main clue, and the treatment at this stage is extremely important, and the combination of Chinese and Western medicines can achieve better results. Chinese medicine treatment of this disease, especially for clinical proteinuria, pay attention to the spleen and kidneys to start. This is because of the prolonged course of diabetes mellitus and the injury to both qi and yin, which affects both spleen and kidney. The spleen belongs to the hexagonal earth, which is responsible for eliminating and transferring the essence to the lungs, and the kidney belongs to the kanshui, which is responsible for hiding the essence and draining the turbidity, and the kidney loses the sealing of the sting, the lower element is not consolidated, and the essence seeps down, resulting in increased foam in the urine and increased clinical protein. Therefore, the treatment is based on strengthening the spleen and kidney, and the medication can be used to strengthen the spleen and kidney to consolidate the root, and at the same time, the patient can be given Che Qian Zi, Ze Xie, and Zu Zu, etc. to facilitate dampness and drain turbidity; Dan Shen, Ze Lan, and Chuan Xiong, etc. to activate blood circulation and remove blood stasis. The combination of Chinese and Western medicine has good clinical efficacy in the stage of microproteinuria and clinical proteinuria in diabetic nephropathy. According to Chinese medicine, diabetic nephropathy is a deficiency of the root and the symptoms of the disease, and patients often have damp-heat, stasis and phlegm gathered in the body at the same time as the deficiency of the root, which can cause the rise of urea nitrogen and creatinine in serious cases. Therefore, the clinical treatment should not only treat the root cause, but also pay attention to the symptoms, focusing on the application of Chinese medicine to resolve dampness and toxicity, reduce phlegm and eliminate blood stasis. In addition to internal consumption, Chinese medicine enema can often achieve twice the effect with half the effort. The formula uses rhubarb to drain turbidity from the internal organs, remove stasis and create new, accelerate the excretion of nitrogen, inhibit the decomposition of nitrogen, improve kidney function, and promote the excretion of endotoxins; calcined oyster is soft, astringent and astringent, rich in calcium carbonate, which can promote calcium intake in the intestine, improve intestinal osmotic pressure, and accelerate the excretion of toxins in the body; Junxue and Tu Fu Ling clear heat and dampness, activate blood and detoxify, play a synergistic role to improve blood supply to the kidneys and reduce kidney damage. . Diabetic nephropathy is a common complication of diabetes mellitus, and its treatment of late dialysis and kidney transplantation brings great physical pain and mental torture to patients. The key to the treatment of diabetic nephropathy is to protect kidney function by treating the reversible stage of early nephropathy. Chinese medicine has great flexibility and individual differences in the treatment of diabetic nephropathy. By combining evidence and disease identification, evidence-based treatment and specific prescriptions and medicines, and combining pharmacotherapy with other therapies, it can better control the disease, delay its progress and improve kidney function.