Multiple lymph nodes in the ileocecal region of the abdomen may be due to causes such as lymphadenitis or appendicitis. It can be treated by medication, surgery and other measures. 1. Lymphadenitis: Lymphadenitis of the abdominal wall may cause multiple lymph nodes in the ileocecal region of the abdomen, and most of them are accompanied by abdominal pain and distension. It can be treated with oral antibiotics such as cefdinir tablets and levofloxacin tablets, as well as analgesic drugs such as ibuprofen and diclofenac sodium. 2. Appendicitis: appendicitis is a common appendiceal disease, will cause the appendix appearance of swelling, congestion, will cause the neighboring lymph nodes enlarged, acute appendicitis once diagnosed, should be timely appendectomy and other surgical treatment measures. It can also be treated symptomatically with antibiotics and drugs to relieve intestinal spasm. It is recommended to go to the hospital for examination to confirm the cause of treatment.