Menstruation does not occur immediately after progesterone, but 3-7 days after stopping the medication. If you do not have a period after 7 days, it is most likely related to pregnancy or estrogen deficiency. It is recommended to go to the hospital for examination and treatment after clarifying the cause. Common causes and treatment 1. Pregnancy: If sexual intercourse exists during ovulation and no contraceptive measures are taken, and menstruation does not come after more than 7 days after stopping the medication, pregnancy can be considered. It is recommended to go to the hospital for blood HCG and ultrasound examination. If the blood HCG value is more than 25mIU/ml or the ultrasound indicates that the gestational sac can be seen in the uterus, it indicates pregnancy; 2. Estrogen deficiency: gynecological ultrasound indicates that the thickness of endometrium is less than 1.0cm, and the six female hormone tests indicate that the level of estradiol is low, it is mostly considered that estrogen deficiency leads to the failure of menstruation, and the simple application of progesterone is ineffective, so it is necessary to perform Progesterone alone is ineffective, and sequential estrogen and progesterone treatment is needed. Daily estrogen supplementation, such as Glivec, can be used for 14 days, followed by progesterone and estroprogesterone treatment for 14 days, and menstruation can come in about 8 days after stopping the drug, but the specific dosage should be used under the guidance of a doctor. If there is blood accumulation in the uterine cavity, ultrasound is needed to check whether there is blood in the uterine cavity. Note: Before taking progesterone, you should consult your doctor in detail about the precautions to be taken and implement them carefully, and if there is discomfort, seek medical attention in time.