Itchy legs, may be related to contact dermatitis, leg eczema, psoriasis, urticaria, venous stasis dermatitis, the main application of drugs for treatment, the cause of the disease is different, the use of drugs is also different. 1. Contact dermatitis: for itchy legs caused by contact dermatitis, antihistamines such as cetirizine and loratadine can be applied as prescribed by the doctor, and antibiotic ointments such as mupirocin ointment and fusidic acid cream can be taken out. 2. leg eczema: leg eczema caused by itchy legs, can be localized external pimecrolimus cream, tacrolimus ointment and other drugs, is conducive to play an anti-allergic, anti-inflammatory, anti-itching effect, if necessary, need to be guided by the doctor to apply methylprednisolone, prednisolone and other glucocorticoid drugs, to control the condition. 3. Psoriasis: psoriasis caused by itchy legs, can be applied to salicylic acid ointment, carbotriol ointment and other topical drugs, if necessary, with the application of oral drugs such as methotrexate, to play an anti-inflammatory role, reduce clinical symptoms. 4. Urticaria: When urticaria exists, topical glycerine lotion can be used to improve the symptoms of itching, and when the symptoms are more serious, hydrocortisone butyrate, mometasone furoate and other corticosteroid hormone ointment can be applied, but also with oral levocetirizine hydrochloride and other drug therapy. 5. venous stasis dermatitis: for venous stasis dermatitis, mometasone furoate cream, hydrocortisone butyrate ointment and other medications, when secondary bacterial infections, can be combined with the use of antibiotic drugs, such as amoxicillin, cefaclor and so on. During the treatment period must follow the doctor’s instructions, reasonable use of medication treatment, do not unauthorized use of drugs.