The general manifestation of depression in adolescents is mainly characterized by low mood, but because of individual differences, some cases also have mood changes such as anxiety and irritability, and serious cases will have physical abnormalities and even suicidal tendencies. 1. Low mood: the most important clinical manifestation of depression, patients are usually sad and pessimistic about things, unable to produce positive emotions such as happiness and pleasure, and usually have a decline in responsiveness. 2. Anxiety, irritability: some cases of irritability, often alternating with low mood, anxiety about what may happen in the future, easily stimulated by certain things around, sudden outbursts of anger, and then quickly enter a negative state after the attack. 3. Physical abnormalities: such as decreased appetite, decreased libido, etc., often accompanied by insomnia and weight loss. 4. Suicidal tendency: when patients fall into serious pessimism, despair, often self-injury or attempted suicide, the reality of all the bad attributed to their own, there may be slit wrists or jumping off a building and other suicidal behavior. If you suspect that teenagers have depression, it is recommended to seek timely medical treatment, standardized treatment under the guidance of the doctor to avoid aggravation of the condition and tragedy.