Tetanus shots include tetanus antitoxin and tetanus human immunoglobulin, which work and neutralize the tetanus toxin, thereby preventing Clostridium tetani infection. In general, people who have traumatic injuries with narrow and deep wounds, or who have been contaminated by soil or other contaminants, and who are at risk of contracting Clostridium tetani infection, should receive the injection as soon as possible after the injury. After injection of tetanus antitoxin, there may be chest tightness and shortness of breath, drop in blood pressure, rapid pulse, nausea and abdominal pain, which in severe cases may lead to anaphylactic shock, urticaria, fever, proteinuria and other serum sickness and other adverse reactions; therefore, those who are allergic to this drug should be prohibited from using it, and allergy tests can be conducted before use. Tetanus human immunoglobulin injection is generally no adverse reactions, some of the injected people may have local redness, swelling, pain, but generally do not need to deal with. Tetanus injection generally need to be used under the guidance of a doctor, if there are related adverse reactions, should be immediately rescued.