Infantile spasms is a specific type of epilepsy syndrome. The child has spasticity, developmental delays, and specific EEG findings. The onset of infantile spasms is usually within 1 year of age, usually between 4 and 8 months of age. The main manifestations are rapid, repetitive, symmetrical spasms of the limbs and trunk lasting 1-2 seconds, occurring in bunches, and occurring multiple times throughout the day. Other manifestations include head nodding, neck tilting, sudden haunches while sitting, etc. There may be crying during or after the seizure. Most seizures stop spontaneously by age 5, but other forms of seizures may occur. Common causes are perinatal hypoxia, abnormal brain development such as tuberous sclerosis, genetic metabolic disorders, etc. Some causes are not found. I. How to treat? 1. Glucocorticoids: preferred, short-term effective, with some side effects ACTHT intramuscular injection or prednisone oral. 2, antiepileptic drugs: long-term application, with certain side effects, need to be gradually adjusted The commonly used ones are Toltea, sodium valproate, etc. 3.Surgery can be considered for intracranial lesions such as nodules, but it must be under the premise of not damaging important functions. Second, the prognosis? It is directly related to the cause of spasticity. Spasticity: mostly stops around 2-4 years old, but other forms of seizures appear in half of the children. Intelligence: most (60%) have neurological damage before the onset, intelligence is already affected, and intellectual development can be halted or even regressed during the seizures. For those with normal development before the onset, 10-20% will later have normal intelligence, and the rest will have mild impairment. The earlier the convulsions are controlled, the less the impact on intelligence. III. Diagnosis? The EEG has a very typical and specific presentation – peak rhythm disturbance. An MRI may reveal abnormalities. If the MRI is normal, an inherited metabolic disorder may need to be ruled out.