A blood culture result of sterile growth usually indicates that no bacteria are present in the blood of the test subject. In the clinic, blood culture is mainly used to detect the presence of some bacteria, such as E. coli, streptococcus, etc., in the subject’s blood, so when the culture result is aseptic growth, it means that the blood does not contain bacteria, i.e., to a certain extent, it can exclude the possibility of certain diseases, such as bacteremia. However, blood culture results of sterile growth cannot exclude all diseases. For example, when pneumonia combined with acute respiratory distress syndrome occurs in a small number of people, the result of no bacterial growth may also occur in the early stage due to the limited inflammatory exudation produced by the pneumonia, and the bacteria have not yet entered the bloodstream. Negative blood cultures can also occur if antipathogenic microbial therapy is administered prior to culture. In addition, there is a certain probability of false-negative results in blood cultures, which should be analyzed in the context of the disease and may need to be reviewed if necessary.