Grade 3 hypertension is defined as a patient’s systolic blood pressure ≥180 mmHg and/or diastolic blood pressure ≥110 mmHg, which is very harmful and requires prompt medical attention. Grade 3 hypertension, i.e., severe hypertension, has the potential to cause various target organs such as heart, kidney, brain, and arterial vascular disease. Therefore, it is important to provide timely intervention and treatment for grade 3 hypertension with close follow-up. Grade 3 hypertension can be treated by lifestyle improvement, such as low-salt and low-fat diet, as well as long-term and reasonable use of oral medications such as amlodipine and enalapril, etc. However, there are many types of blood pressure-lowering medications, so you need to choose the most suitable medication for you under the guidance of your doctor to maintain your blood pressure at a stable level. Attention to regular follow-up, in which to monitor the blood pressure, heart rate and whether the target organs caused by hypertension damage, the emergence of discomfort in a timely manner to consult the doctor.