The process of cold and runny nose is from a large amount to a small amount, the nasal mucus from the clear nasal mucus gradually become sticky, such as secondary infection, yellow nasal mucus can appear, the specific process has some individual differences. Cold is a kind of upper respiratory tract infection, caused by viral infection, which can lead to the patient’s nasal mucosa congestion, edema, exudation and other inflammatory reactions, thus causing the symptoms of runny nose. In the early stage of colds, patients often show nasal congestion, clear nasal discharge and a large amount of nasal discharge, after which the nasal discharge begins to become thick and sticky, and finally gradually reduced, usually in 7 to 10 days to heal. If combined with or secondary to a bacterial infection, the symptoms of a yellow runny nose may occur. When the symptoms of cold and runny nose are serious, you can follow the doctor’s instructions to give the nasal mucosa vasoconstrictor (ephedrine nasal drops), glucocorticoids (budesonide nasal spray) and other medications, which can reduce the congestion of the nasal mucosa, reduce the exudate, and alleviate the symptoms of runny nose. For bacterial infections, antibiotics such as amoxicillin can be targeted for treatment. The use of drugs should be under the guidance of a professional physician to avoid adverse consequences.