Squamous epithelial papillomatous hyperplasia is usually not self-extinguishing and requires treatment. Squamous epithelial papillomatous hyperplasia is a pathologic finding that indicates the presence of benign papillomatous hyperplasia, more commonly known as condyloma acuminatum, a human papillomavirus, or HPV, infection transmitted through sexual contact, and condyloma acuminatum is generally not self-extinguishing once it forms. Physical therapy is generally recommended for smaller numbers and sizes of warts, which can be removed by laser, cryo-electrocautery and other methods. For a larger number of acromegaly, surgical treatment is necessary, but these treatments can not eliminate the HPV virus from the root, but only eliminate the symptoms. HPV virus infection has a certain recurrence, during the treatment period should be appropriate exercise, enhance the body’s resistance, to prevent recurrence. Squamous epithelial papillomatous hyperplasia, should be under the guidance of the doctor to choose the appropriate treatment, do not expect self-healing, to avoid delaying the condition.