Irritable bowel syndrome has a complex etiology and is recurrent, requiring a combination of treatments to effectively cure it, usually depending on the individual. Clinically, it is characterized by abdominal pain, abdominal discomfort, changes in bowel habits and changes in stool properties, and often coexists with other functional diseases of the gastrointestinal tract such as gastroesophageal reflux disease and functional dyspepsia: 1. For constipation and bloating, eat more fiber-rich foods that are not easily flatulent. Also do not overeat and do not snack. Patients with mainly diarrhea should eat less food containing coarse fiber, such as corn, celery, etc., and eat more fresh fruits and vegetables rich in vitamins and proteins, such as kiwi, oranges, etc.; 2. Psychotherapy: the emergence or aggravation of irritable bowel syndrome has some relationship with mental factors. Patients often clinically show anxiety, depression and other disorders. Relieving patients of many doubts, eliminating fears and improving confidence in overcoming the disease can help a lot in the treatment of the disease; 3. However, the premise is that medication should be used under the guidance of a doctor, such as paroxetine, amitriptyline and other antidepressant and anxiolytic drugs, which can effectively block the vicious circle between the somatic symptoms of irritable bowel syndrome and psychological disorders. In order to treat diarrhea, drugs such as scopolamine, benactyzine, loperamide and probiotic preparations can be used to inhibit the growth of pathogenic bacteria, correct the dysbiosis of intestinal flora, restore and maintain the stability of the intestinal microbial ecosystem; drugs such as cisapride and lactulose can be used to increase gastrointestinal propulsion and promote defecation, but should be used with caution for those with allergies; hormones and peptide-related therapy can be used to enhance contractile bowel movements In addition, oral montelukast and injectable leuprolide acetate can be used to prevent intestinal epithelial cell damage, absorb intestinal gas, and reduce intestinal sensitivity.