Ritovastatin should refer to Rosuvastatin, Ezetimibe can be taken at the same time with Rosuvastatin. Clinically, Ezetimibe and Rosuvastatin are both drugs used for lowering blood lipids, their difference is the mechanism of action is different. Ezetimibe mainly inhibits the absorption of cholesterol from the brush border of the jejunal mucosa, and reduces exogenous cholesterol to achieve the purpose of lowering blood lipids; while Rosuvastatin mainly selectively inhibits the HMG-CoA reductase enzyme, which reduces the production of endogenous cholesterol. When ezetimibe is used in combination with Rosuvastatin, the lipid-lowering effect is significantly increased, and the reflex gastrointestinal cholesterol absorption increase caused by Rosuvastatin alone can be avoided. The main adverse reactions of ezetimibe are thrombocytopenia, dizziness, sensory abnormalities, constipation, myalgia, weakness, and allergic reactions. It is contraindicated in patients with hypersensitivity to drug components, active liver disease, and unexplained persistent elevation of aminotransferases. The main adverse reactions of Rosuvastatin are elevated blood glucose, dizziness, headache, abdominal pain, nausea, constipation, myalgia, weakness, etc. Occasionally, itching and urticaria can be seen; contraindicated in patients who are allergic to the components of the drug, patients with active liver disease and unexplained persistent elevation of aminotransferases, patients with severe renal insufficiency, patients with myelopathy, patients using cyclosporine, as well as pregnant women and lactating women. It should be noted that during the use of the drug should be regularly rechecked liver function, once the transaminase is elevated or unexplained myalgia, myalgia should be immediately discontinued, and promptly go to the hospital for medical treatment.