Pain in the buttocks and thigh roots may be caused by excessive exercise, cold environmental stimulation and other factors, or it may be caused by pathological reasons such as pyriformis syndrome and lumbar disc herniation. 1. Physiological factors: the location of buttocks and thigh roots is covered by thick myofascial tissues, prolonged standing and sitting for a long time or excessive exercise may lead to fatigue of myofascial tissues in these areas, resulting in the accumulation of lactic acid, which will stimulate the nerve roots and cause pain; prolonged exposure to cold in the buttocks and thigh roots will cause the contraction of subcutaneous blood vessels, and the above mentioned symptoms may also occur. 2. Pathological causes: the sciatic nerve runs underneath the pyriformis muscle of the buttocks, and the sciatic nerve may be stimulated by pressure or pulling in the pyriformis muscle due to various reasons, such as pyriformis syndrome and sciatic neuritis. Lumbar diseases may also cause compression of the nerves innervating the buttocks and thigh root area, which may also cause the above symptoms, common diseases such as lumbar disc herniation, spinal stenosis and so on. Buttock thigh root pain may also have other causes, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.