Numbness in the hands and mouth is considered to be a symptom of neurological deficit, which can be seen in cerebrovascular disease, intracranial occupancy or craniocerebral trauma, all of which can lead to numbness in the hands and mouth. For numbness of the mouth and hand caused by cerebrovascular disease, the patient mostly has sudden onset, accompanied by dizziness and headache, and in severe cases, numbness of the ipsilateral lower limbs. If it is ischemic cerebrovascular disease, symptomatic treatment can be given to improve circulation, activate blood circulation and remove blood stasis. If it is hemorrhagic cerebrovascular disease, the patient can be given treatment such as dehydration and cranial pressure reduction and surgery according to the amount of bleeding. Secondly, if the numbness of the hands and mouth is a slow-onset and progressive aggravation, it is important to pay attention to whether it is caused by intracranial occupancy. It can be seen in primary tumors and metastases in the brain, and can be accompanied by headache symptoms. After diagnosis, conservative or surgical treatment can be given depending on the size of the lesion. After trauma to the head, the patient may suffer from cerebral contusions, etc. It is recommended to check the CT of the head and to rest in bed.