Lupus erythematosus can be discontinued from hormones on the advice of a doctor after long-term stabilization. Lupus erythematosus is an autoimmune disease with multi-system involvement, and commonly used therapeutic drugs include glucocorticosteroids, such as prednisone acetate tablets. Patients whose condition has been stabilized for a long time can gradually stop using hormones under the guidance of doctors, but they should not stop using them on their own in order to avoid aggravation of the condition. Lupus erythematosus cannot be completely cured at present, and the condition may worsen at any time. Therefore, lupus patients who have stopped taking hormones still need to go to the Rheumatology and Immunology Department every three months or six months to have their conditions evaluated. If patients with lupus erythematosus experience joint swelling and pain, skin rash, double lower extremity edema, etc. during the period of hormone withdrawal, it is recommended to go to the hospital in time to assess the condition and give standardized treatment under the guidance of the doctor, so as to avoid delaying the condition.