The most common anti-inflammatory drugs used to treat toothache are roxithromycin and metronidazole, and patients who are not allergic to cephalosporin can also take cephalosporin and metronidazole orally for anti-inflammatory purposes. If a toothache occurs, it is important to find out the cause of the toothache. Acute pulpitis will cause toothache symptoms, the main thing is to do root canal treatment at this time, take medicine to treat the symptoms but not the root cause, it will only temporarily alleviate the symptoms, will not completely treat the toothache problem caused by pulpitis. The symptoms of dental pulpitis should be treated in a timely manner in order to completely solve the toothache. Acute wisdom tooth pericoronitis can also cause toothache, this time it is necessary to carry out anti-inflammatory treatment, you can take oral roxithromycin and metronidazole to reduce inflammation, together with local rinsing, then wisdom tooth pericoronitis can be quickly recovered. The wisdom tooth should be extracted in time after the swelling and pain of peri-coronitis has recovered, otherwise it will happen again and again. For toothache caused by periodontal abscess, anti-inflammatory treatment is also needed, together with local scraping. This is the only way to completely solve the problem of toothache caused by periodontal abscess. The toothache should not be solved by taking medicine alone, but by examining the cause of the toothache and making specific treatment, so that the toothache can be completely solved.