It is not recommended to drink coffee within a short period of time after rabies vaccination, so as not to affect the immune function of the body or cause other discomforts, and the specific dietary contraindications should be in accordance with the doctor’s advice. Coffee is a stimulant food, which may affect the function of the immune system and interfere with the production of anti-rabies virus immunity; on the other hand, it may cause headache, abdominal pain and other discomforts, which may be confused with the adverse reactions of the vaccination, and is not conducive to the observation of the side effects of the vaccination. Therefore, it is prudent not to drink coffee after rabies vaccination for a short period of time (generally 1~2 weeks, the specific length of time can be adjusted according to the doctor’s advice), in order to ensure the successful completion of the immunization program, after which normal drinking can be resumed. It is also important to note that rabies vaccine is indicated for post-exposure immunization in case of bites and scratches from rabid dogs or other rabid animals, or pre-exposure immunization when there is a risk of exposure to the rabies virus. There are no contraindications to the former, while the latter is contraindicated in people who are allergic to this vaccine, as well as in the presence of conditions such as fever and severe chronic diseases. Adverse reactions such as discomfort at the injection site, fatigue, headache, etc. may also occur after vaccination. To summarize, those who have rabies vaccination needs must carry out standard operation under the guidance of doctors, and must not blindly dispose of it by themselves, so as to avoid adverse consequences.