Preparation for pregnancy needs to take folic acid, is conducive to the prevention of fetal neural tube malformation, improve the quality of sperm and egg. Folic acid can promote cell division, promote the development of the nervous system, can prevent fetal neural malformations, eat folic acid before pregnancy, can let the female body folic acid amount to maintain a certain concentration, so as to provide better nutritional environment for the early development of the embryo, pregnancy, if possible, can be supplemented with folic acid throughout pregnancy. The process of sperm and egg production requires protein synthesis and the participation of pyrimidines and purines. Supplementation of folic acid will improve the function of the testes and ovaries, and improve the quality of sperm and eggs. Flushing, nausea, loss of appetite, flatulence, bitter or unpleasant taste in the mouth, and sleep problems may occur during the course of the medication, which should be taken according to dosage as prescribed by the doctor. Clinical guidelines recommend folic acid supplementation during the first trimester and throughout pregnancy, as well as good lifestyle habits, balanced diet and proper exercise, and timely medical consultation with a healthcare professional if there is any discomfort.