Gitelman Syndrome refers to Gitelman Syndrome, which has a wide range of symptoms, the more common ones being weakness of limbs, chondrocalcinosis, polyuria and so on. 1. Weakness of limbs: Gitelman syndrome is a hereditary gene mutation, further aggravation of the disease will lead to abnormalities in renal tubular and glomerular function, and patients often have hypokalemia. If not replenished in time, it will affect the limbs, resulting in weakness and abnormal activities. These patients need to maintain sufficient physical ability to live a normal life. 2. Chondrocalcinosis: Some patients with Gitelman syndrome may develop calcification of articular cartilage, which is associated with hypomagnesemia, and may be related to decreased pyrophosphatase activity and interference with pyrophosphate crystallization. 3. Polyuria: Gitelman syndrome may manifest as polyuria, nocturia, enuresis, proteinuria, etc. It is mainly associated with hypokalemic nephropathy. Gitelman syndrome symptoms are many and atypical, it is recommended to have any discomfort, regular hospital visits, standardized examination and treatment under the guidance of physicians.