Chronic osteomyelitis generally has little impact on a person’s normal life expectancy, depending on the severity of the disease and the patient’s physical and nutritional status, among other factors. The onset of chronic osteomyelitis is usually the result of poor treatment of acute osteomyelitis, which gradually evolves into a chronic inflammatory response, mostly manifested as vague pain in the lesion area, aggravated by exertion and relieved by rest, some of which may require long-term oral analgesics to relieve pain. Usually, chronic osteomyelitis does not have a significant impact on normal life expectancy. If combined with other diseases, such as malnutrition, tuberculosis, tumors and other wasting diseases, chronic osteomyelitis may have some impact on life expectancy, the exact duration of which varies from person to person and cannot be generalized. It is important to protect the bones from external forces during the disease, as fractures are difficult to heal and can be difficult to treat, with a poor prognosis.