HIV is no longer an incurable disease, and with successful antiviral treatment, the vast majority of patients can live largely unaffected by life expectancy. More and more young HIV-infected people are planning to have a healthy child. Today I will talk about ways to have a child with a positive male partner and a negative female partner. Internationally, the male partner is treated with antiviral therapy, and when the viral load is undetectable semen is taken for sperm washing, the semen is removed leaving the sperm (the semen may have the virus in it but the sperm is not infected with the virus) and artificial insemination or IVF is performed. There are no hospitals in China that do sperm washing for HIV patients, so there is no formal recommended method medically for this condition in China. However, we have patients who have conceived naturally without sperm washing, during the female partner’s ovulation period, and the female partner then takes blocking drugs, and nearly 100 cases have been successful. However, it is important to note that this is not recommended by the doctor because of the risk, although the risk of sexual transmission is very low when the viral load is not detected. It is also important to note that both partners need to go to the hospital to have their reproductive function tested before having a child, and only if the reproductive function is normal will success be possible. If there are already abnormalities in reproductive function (which are not known because they are not tested), repeated unprotected sex increases the risk of infection to the woman and makes successful conception impossible. For cases where the woman is not too old (say less than 35 years old), I would suggest not rushing for now and wait and see. Maybe sperm washing will be given to positive people in China, maybe new research data will be published, maybe better blocking drugs will be available. After all, there is still a risk of natural conception, albeit a small one.