Why can selenium supplementation prevent liver disease what are the side effects of selenium yeast tablets? Selenium combines with liver disease free radicals and membrane proteins and enzyme proteins to reduce the antioxidant and protein content in liver cells, thus affecting the metabolism of things in liver cells, if liver cells are in this unfavorable environment for a long time, external viruses and carcinogenic chemicals will be more likely to invade liver cells, and liver lesions will accelerate. At this time the human body needs to remove these excess free radicals. Selenium is an effective thing to scavenge free radicals, it can scavenge free radicals directly, but also can reverse the regulation of enzymes closely related to the growth of liver cells, to protect liver cells; at the same time, selenium is the active component of glutathione peroxidase, the increase in plasma concentration of selenium, glutathione peroxidase activity significantly increased, both in the body with the role of scavenging free radicals, to protect liver cells from peroxidation Both have free radical scavenging effects in vivo and protect liver cells from peroxidation damage. In short, selenium has anti-cancer, prevent the formation of excessive collagen fibers, prevent liver necrosis and other hepatoprotective effects. Selenium and hepatitis in daily life, due to internal and external environmental imbalance, often present liver disease, the most common is hepatitis, especially the disease http://baotaostore.info毒性肝炎,因是传染性疾病,常常是一人抱病,使全家以及左右的邻居不宁. Hepatitis is a liver disease caused by one of the five or more viruses, has caused harm to human health, according to the U.S. Business Week (1994.4.4 issue) reported that hundreds of millions of people suffer from this disease every year, 2 million people died from this disease. There are 300 million hepatitis B virus carriers in the world, 75% of them are in the Far East, and 100 million of them are in China. Faced with this reality, medical professionals in China have made great efforts to prevent and treat hepatitis, especially in the use of selenium to prevent and treat hepatitis. Firstly, it was found and proved that the blood selenium level of hepatitis patients was significantly lower than that of healthy people. Then with various methods of selenium supplementation have achieved promising results in the treatment of hepatitis, the famous expert Yu Shuyu of the Institute of Oncology of the Chinese Academy of Medical Sciences led the scientific research team to Qidong County, Jiangsu Province as the scene, after 16 years of hardship, dedicated to the study of the impact of selenium on liver cancer and the occurrence of hepatitis, the people of Qidong County have participated in the state affairs of the right township of more than 20,000 people in the implementation of electronic cigarette list selenium supplementation, continuous observation for three years, found that the people have participated in the right township of hepatitis The incidence of hepatitis in Qidong County was significantly lower than that in the six surrounding control villages, and the incidence of hepatitis decreased by 56%. Yu Tianzhen et al. (1996) treated 50 cases of hepatitis patients, 39 cases were clinically cured and 7 cases were improved, the cure and improvement rate was 92%, and the efficacy was significantly higher than that of the control group. Yuan Kesheng et al. (1996) treated 60 cases of chronic hepatitis, cured 43 cases, improved 12 cases, the cure rate also reached 92%, the efficacy is significantly better than the control group, indicating that the treatment of viral hepatitis with selenium preparations jaundice subsided quickly, reduce the transaminase effect is good. We also learned from the treatment of refractory chronic hepatitis in addition to other hepatoprotective drugs on the basis of selenium preparations, the effect is better. The scientific community generally believes that hepatitis destroys the function of liver tissue processing waste, while selenium scavenges free radicals through glutathione peroxidase and prevents lipid peroxidation, avoiding destructive oxidation of lipids on cell membranes, microsomal membranes and lysosomal membranes by peroxides, thus protecting the integrity of cell membranes, invariance and normal physiological functions of cells. Protected the liver. The more serious the liver disease, the lower the blood selenium value Modern scientific research has found that when the liver presents disease, the more serious the disease, the lower the selenium level in the blood. Such as hepatitis B surface antigen healthy carriers, acute hepatitis. Chronic prolonged hepatitis, chronic active hepatitis, heavy hepatitis, hepatic steatosis, and even liver cancer patients, the blood selenium level decreases sequentially and is significantly lower than that of normal control population (Wang, 1994, Huang, 1996). For this objective fact in real life, medical scientists have carried out many in-depth researches and constantly found that the hepatitis virus has a direct damaging effect on hepatocytes themselves after invading people’s body, and more selenium is needed to protect hepatocyte membrane structure and function. With the significant decrease of selenium level and glutathione peroxidase activity in liver tissues, it is not entirely possible to scavenge excess free radicals and prevent lipid peroxidation, which further promotes the damage of hepatocytes by autonomous radicals and lipid peroxide. In the absence of timely rest and treatment, especially in the absence of timely selenium supplementation, the liver disease will worsen. It is no wonder that the risk of liver cancer in patients with a history of hepatitis is three times higher than that in those without a history of hepatitis. For patients with hepatitis with low selenium, early selenium supplementation is a feasible new prevention and treatment pathway to improve the disease and prevent the occurrence of cancer. The Institute of Oncology, Chinese Academy of Medical Sciences has prevented primary liver cancer through selenium supplementation in high-risk groups. The hepatitis B surface antigen carriers were given selenium yeast tablets orally, and 200 micrograms of selenium was taken daily. After 4 years of continuous observation, none of the selenium-supplemented patients had liver cancer, while 37 cases of liver cancer occurred in the control group. The relative risk of liver cancer in the control group was 2.36-2.52 times higher than that in the selenium-supplemented group, and the same result was obtained that selenium supplementation could prevent liver cancer. The liver function and kidney function of both the selenium supplementation group and the control group were tested every other month during the experimental period for 2 years, and no difference was found between the two groups after statistical treatment, indicating that oral selenium 200 micrograms per day is safe and feasible.