At present, there is no data to show which drug has the best effect in lowering high uric acid, the main clinical drugs to lower uric acid are: drugs to inhibit uric acid production: these drugs reduce the production of uric acid by inhibiting xanthine oxidase, and are suitable for those who produce too much uric acid or are not suitable for using uric acid excreting drugs. However, patients with renal insufficiency should reduce the dosage appropriately, and patients with uremic phase should be prohibited. Uric acid-removing drugs: commonly used are benzbromarone. These drugs can inhibit urate reabsorption, thus increasing uric acid excretion and reducing uric acid levels. It is indicated for those with good renal function and it is important to drink more water and take sodium bicarbonate during the medication. Alkaline drugs: such as sodium bicarbonate, can alkalize the urine, so that uric acid is less likely to gather and form crystals in the urine. New uric acid-lowering drugs: ① uric acid oxidase, which breaks down uric acid into soluble products for excretion; ② selective uric acid reabsorption inhibitors. In addition, patients with hyperuricemia should also pay attention to: ① pay attention to diet control; ② limit alcohol consumption and large intake of high-purine food; ③ drink a lot of water to increase uric acid excretion; ④ carefully use drugs that inhibit uric acid excretion such as thiazide diuretics; ⑤ try to avoid various triggering factors and actively treat related diseases. Therefore, the drugs to lower uric acid, suitable, do not rely only on these drugs, but also according to their own causes and conditions to choose Chinese medicine, and in addition to drug treatment should also pay attention to its diet regimen, physical therapy, so that comprehensive treatment to achieve better results.