The modern medical concept of rheumatoid disease refers broadly to a large group of diseases affecting bones, joints, muscles and their surrounding soft tissues, such as bursae, tendons, fascia, blood vessels, and nerves. Rheumatoid diseases are diseases that mainly affect joints, muscles, bones and soft tissues around joints, such as tendons, ligaments, bursae, and fascia. Commonly, there are autoimmune connective tissue diseases, systemic vasculitis, lesions of bone and joints, so the common symptoms are: 1. Pain is the main symptom of rheumatoid disease, which can be manifested as local pain, generalized pain, joint pain and muscle pain. Pain can be acute onset or slow onset, the degree of pain can be very intense, or very mild, or only manifested as discomfort, soreness or numbness. Pain is often triggered or aggravated by cold or wind; non-trauma-induced joint swelling and pain is often a manifestation of rheumatoid disease. Joint pain, neck and shoulder pain, low back pain, and heel pain are often common manifestations of rheumatoid disease, sometimes accompanied by swelling of the joints and a feeling of stiffness in the morning. Rheumatoid arthritis often has symmetrical joint swelling and pain, especially in the proximal interphalangeal joints, metacarpophalangeal joints and wrist joints; ankylosing spondylitis has low back pain, heavy pain at night, in the morning and at rest, but improves after a little activity, and can be accompanied by heel pain and uveitis; joint pain caused by gout, often at night, severe pain like cutting, pain peaks within 24 hours, most often in the joints of the foot, single Joint onset, accompanied by local swelling and redness; muscle weakness accompanied by muscle pain and elevated muscle enzymes are common in polymyositis/dermatomyositis, systemic lupus erythematosus, etc. 2. Fever is a common symptom of rheumatoid disease, which can be low fever, moderate fever, or high fever, often manifesting as irregular fever, along with fast blood sedimentation, but usually without chills, ineffective antibiotic therapy and effective hormone therapy. Such as systemic lupus erythematosus, adult Still’s disease, lipofuscinosis, etc. can be fever as the first symptom. 3. Skin and mucous membrane manifestations SLE, polymyositis/dermatomyositis, leukodystrophy, seborrhea, and dry syndrome can have facial or generalized rash, sun allergy to sun-exposed skin, red and itchy skin, rash, etc., dry mouth, dry eyes, oral ulcers, vulvar ulcers, ocular uveitis, skin nodules, skin ulcers, etc. 4, Raynaud’s phenomenon excessive physical exercise leads to muscle groups produce lactic acid accumulation, massage helps lactic acid as soon as possible by the blood absorption and metabolism. The method is to pinch with your hand or gently tap the calf with your fist. Thighs and arms, shoulders, is the muscle to relax. 5, multi-organ damage Some rheumatoid diseases, especially autoimmune connective tissue diseases such as systemic lupus erythematosus, rheumatoid arthritis, dry syndrome, etc. can have multiple organ damage, such as manifested as cardiac inflammation pericarditis, myocarditis, endocarditis, kidney damage proteinuria, hematuria, swelling, hypertension, renal failure, hematologic system leukopenia, erythrocyte reduction, thrombocytopenia, hemolysis, etc. Respiratory system interstitial pneumonia, pulmonary hypertension, pleural effusion, digestive system liver function impairment, jaundice, etc. 6.Other Unexplained hematuria and proteinuria are commonly seen in systemic lupus erythematosus; unexplained leukopenia, thrombocytopenia and/or anemia are commonly seen in systemic lupus erythematosus, dry syndrome, etc.