The differential diagnosis of urticaria and eczema is made in the following aspects: a. Urticaria usually manifests itself as a variable-sized, variable-form wind-blown mass or edematous erythema, with no trace of the rash after it subsides, accompanied by characteristic manifestations of the skin-scratching sign category. Eczema has a polymorphic rash, including erythema, papules, maculopapular rash, papules, blisters, vesicles, exudates, crusts, etc. Second, the etiology, urticaria can be due to genetic factors, mental stimulation factors or medical diseases and other factors. Eczema can be caused by allergic factors or drug stimulation and other factors. In terms of treatment, urticaria can be coated with glyburide lotion and eczema can be coated with glucocorticoid drugs such as Denide ointment.