Does metronidazole damage kidney function?

Metronidazole is a type of antibiotic that usually has no significant impairment of renal function when taken normally.
Metronidazole is commonly used clinically for the treatment of anaerobic infections, intestinal and extra-intestinal amebiasis, vaginal trichomoniasis, cutaneous leishmaniasis, and guinea worm infections.
Common adverse reactions of metronidazole are gastrointestinal reactions, including nausea, loss of appetite, vomiting, etc.; other adverse reactions can be seen headache, dizziness, numbness of the limbs; a few patients may develop urticaria, pruritus, metallic taste in the mouth and leukopenia. The above adverse reactions recover spontaneously after stopping the drug. Avoid drinking alcohol while taking the drug. Contraindicated in patients with active central nervous system disorders and blood diseases.
If patients need to apply metronidazole, it is recommended to use the drug under the guidance of a doctor, avoid self-medication to avoid adverse effects.