Antigen reagents from different manufacturers should not be mixed. Differences in their composition may result in invalid samples or erroneous results. Antigen reagents from different manufacturers cannot be mixed. Antigen reagents are meant to be mixed thoroughly and used when performing tests. Due to differences in specific formulations between manufacturers, they are generally designed for their own products and therefore differ slightly in their effectiveness. Mixing may result in sample failure, and collectors from the same manufacturer may require matching reagents. At the same time, the required concentration may not be achieved after mixing, which may affect the final test results. Therefore, it is not recommended to mix the samples, but to ensure the validity of the results, it is necessary to use the matching reagents.