Generalized soreness and coldness are firstly considered diseases such as viral cold, hyperthyroidism, rheumatoid arthritis and so on; they may also be caused by exertion, strenuous exercise and other conditions. 1. Disease causes: (1) Viral cold: it causes muscle aches and chills symptoms due to fever, and it can also have symptoms such as fatigue, nausea, headache, dizziness and fever. (2) Hypothyroidism: It is mainly due to abnormal function of the thyroid gland, which leads to slowing down of body metabolism and symptoms of muscle aches and chills. It can also be accompanied by symptoms such as fatigue and drowsiness. (3) Rheumatoid arthritis: it can be accompanied by low fever, joint swelling and pain, fatigue, etc. Joint pain and soreness are more obvious when the temperature drops, and it is characterized by fear of cold and love of heat. 2. Exhaustion, strenuous exercise: when you are tired or exercise strenuously, your body will produce a lot of lactic acid, and if the lactic acid is not metabolized sufficiently, muscle pain and other symptoms will occur. Due to exertion, strenuous exercise will have a certain amount of sweating, sweat evaporation will be afraid of cold. If the symptoms of generalized soreness and chills persist without relief, it is recommended to consult a doctor for clarification in conjunction with relevant examinations.