SLE is one of the more dangerous types of rheumatic immune diseases and used to have a high mortality rate, but with the improvement of treatment, the prognosis of this disease has improved significantly and the average survival of patients has increased greatly. Because SLE can cause irreversible damage to important organs of the human body and damage physical functions, it was once considered a disease with high mortality rate in history. For example, in the 1950s, the 4-year survival rate of SLE patients was only 50%. However, with the increase of early diagnosis methods and the improvement of treatment level, the 10-year survival rate of SLE patients has reached 90% and the 15-year survival rate can reach 80%, and most patients can work and live like normal people. However, it should be pointed out that due to the complex and diverse clinical manifestations of SLE, the severity of the disease varies from patient to patient. For patients with acute onset, rapid disease progression, heavy lupus with severe damage to several important organs, or lupus crisis, the disease is more dangerous and still has a certain mortality rate. Therefore, SLE has gradually changed from an explosive, uncontrollable and lethal emergency to a chronic and controllable disease. For most patients with SLE, after early diagnosis and systematic and standardized treatment, the prognosis is better and the survival rate is higher.