A pediatrician cannot withstand a high fever of 48°C in the first place. If the fever is simply high, it will not directly cause brain damage and affect intelligence. Generally speaking, there is an upper limit to the high fever that the human body can withstand, and a fever of more than 40 ℃ is already a critical situation. In addition, high fever is not the culprit that leads to brain damage after fever and affects intelligence, but mainly in cases of meningitis, intracranial infections and other conditions that cause irreversible damage to the brain function and lead to a decline in intelligence. Children’s immune system and various protective barriers are in the stage of rapid development to maturity, the occurrence of high fever may be one of the manifestations of bacterial or viral infections, fever shows that the body in the tenacious fight and does not directly damage the brain function. It is recommended that children with fever consult a doctor in time, improve the relevant examination to clarify the cause of the disease to be targeted treatment or treatment, so as to avoid delaying the condition.