A little pain in the testicles when pressed may be testicular inflammation, prostatitis, epididymitis, varicocele and so on. 1. Orchitis: testicular infection caused by bacterial or viral infection, manifested as redness and swelling of the scrotum, testicular pain, and accompanied by testicular pressure pain. 2. Prostatitis: prostatitis may also lead to testicular pressure pain, the most common cause of pain, especially chronic prostatitis, may also be accompanied by pain in the penis, inner thighs, perianal area and other parts of the body. 3. Epididymitis: Epididymitis may also cause testicular pressure and pain, as well as swelling in the scrotum, discomfort, distension, and other symptoms. 4. Varicocele: Patients with varicocele may experience scrotal discomfort, scrotal pain and testicular pain. There may also be other causes, patients are advised to go to the hospital in time to clarify the cause of the disease and then treated.