Mouthwash containing a long time mucous membrane detachment can be discontinued first, every day to maintain oral hygiene and sanitation, serious cases can use recombinant bovine alkaline fibroblast growth factor gel and other drugs. Oral mucosa is a layer of stratified flat epithelium and lamina propria covering the oral cavity. There is no mucosal muscular layer, which contains a large number of glands. Some mouthwashes contain sodium dodecyl sulfate, the use of which can appear simple oral mucosal detachment, not accompanied by congestion and erosion, without pain and other self-conscious symptoms. Need to stop using toothpaste or mouthwash containing sodium dodecyl sulfate, remove bad restorations, maintain oral hygiene, etc., oral mucosa can gradually grow out. If the severe condition is accompanied by pain, lidocaine gel and recombinant bovine basic fibroblast growth factor gel can be used as appropriate to relieve symptoms and promote mucosal growth. It is recommended to use mouthwash and then gargle with water for 2 to 3 minutes to prevent mouthwash residue from dislodging the oral mucosa. When the condition is serious, it is recommended to go to a specialized hospital in time and standardize the treatment. The above drugs should be used under the guidance of a doctor.