Some people, after taking Colla Corii Asini, may show signs of hyper-fire, such as many hot sores on the nose, mouth and lips, or dry eyes, redness, increased eye mucus, or even dry and sore throat, constipation or blood in the stool, etc. The above symptoms are caused by taking fresh Colla Corii Asini. Due to the limitation of the existing production process, the freshly made Colla Corii Asini always carries some fire toxicity, thus the consumption of fresh Colla Corii Asini can cause hyper-fire and various poisoning symptoms. According to the theory of Chinese medicine, freshly made Colla Corii Asini should not be taken, but should be kept in a dry place for more than three years until the fire toxicity is eliminated by itself. Colla Corii Asini is nourishing and greasy, it may cause indigestion. Women should not take Colla Corii Asini during menstruation, as it is a blood tonic and hemostatic, it may cause a large increase in menstrual flow and shorten menstruation in sensitive individuals. This product should be taken before meals. Avoid oily food during the consumption of Colla Corii Asini. It should not be taken by patients with colds, pregnant women, hypertensive patients, diabetic patients under the guidance of physicians, and children under the guidance of physicians. If symptoms do not improve after two weeks or during the dosing period, or if symptoms worsen, or if new serious symptoms appear, stop taking the drug immediately and go to the hospital. It is prohibited for those who are allergic to this product and should be used with caution for those with allergies.