Locally advanced invasive breast cancer mainly refers to breast cancer where the lesion is confined to the breast and its surrounding tissues for metastasis. Locally advanced invasive breast cancer mainly refers to the primary lesion is relatively large, usually there has been regional lymph node metastasis. For example, an enlarged lymph node can be felt in the armpit, but there is no evidence of distant metastasis, so the lesion is still relatively confined to the breast and its periphery, and there is hope for a cure, so it is called locally advanced invasive breast cancer. The prognosis of locally advanced invasive breast cancer is better than that of advanced breast cancer with distant metastasis, but locally advanced breast cancer is not as good as early stage, or even better than intermediate stage breast cancer, which has higher probability of potential distant metastasis, so it must be taken seriously. Active diagnosis and treatment, for lesion control, and then further consider surgical treatment. Therefore, patients with locally advanced invasive breast cancer should go to the hospital in time for early treatment to avoid delays.