Treatment of uterine fibroids

  Uterine fibroids (hereafter referred to as fibroids) are a common and frequent disease in women. The size of fibroids varies widely, from the smallest microscopic fibroids to those exceeding the size of a full-term pregnancy; their symptoms are also variable, and their growth sites vary depending on whether they are fertile or not, so there are various treatment methods, including expectant therapy, medication, and surgery (including conservative surgery and radical surgery, and the surgical approach and methods are individualized from person to person). It can be seen that not all myomas need to be treated surgically.  I. Expectant therapy Expectant therapy has its unique advantages and is becoming more and more accepted. Expectant therapy is mainly suitable for fibroids of 12 gestational weeks in the uterus.  Medication Medication is an important measure for the treatment of fibroids and can be considered for: 1. women with fibroids less than 2-2.5 months of gestation, with mild symptoms and near menopausal age; 2. women with large fibroids who require preservation of reproductive function and avoid excessive uterine size and incision; 3. women with fibroids causing excessive menstruation, anemia, etc. who can be considered for surgery but are unwilling to undergo surgery and are 45-50 years old; 4. women with large fibroids who are ready for transcatheter surgery. Women with large fibroids who are ready to be removed by cathodic or laparoscopic or hysteroscopic surgery; 5. Women who want to correct anemia and avoid intraoperative blood transfusion and complications before surgical removal of the uterus; 6. Women with fibroids combined with infertility who need medication to shrink the fibroids and create conditions for conception; 7. Women with medical comorbidities who cannot undergo surgery. Contraindications are: 1. fast growth of myoma, malignancy cannot be ruled out; 2. degeneration of myoma, malignancy cannot be ruled out; 3. obvious symptoms of submucosal myoma, which affects conception; 4. reversal of subplasma myoma; 5. myoma causing obvious compression symptoms or pelvic entrapment of myoma, which cannot be reset.  Surgery is still the main treatment method for myoma.  1.Transcatheter hysterectomy: It is suitable for patients who have no fertility requirement, uterus ≥ 12 weeks gestation uterus size; excessive menstruation with hemorrhagic anemia; fast growth of myoma; symptoms of bladder or rectal compression; failure of conservative treatment or recurrence of myoma after enucleation, and large tumor or serious symptoms.  2. Transvaginal hysterectomy: suitable for those who have no pelvic adhesions or inflammation and no masses in the adnexa; those who want to have no scars in the abdomen or obese abdomen; those whose uterus and fibroids do not exceed the size of 3 months of pregnancy; those who have uterine prolapse can also have transvaginal hysterectomy and pelvic floor reconstruction; those who have no history of previous pelvic surgery and do not need to explore or remove adnexa; those who have fibroids with diabetes, hypertension, coronary artery disease, obesity and other medical conditions. Those who cannot tolerate open surgery due to comorbidities.  3.myomectomy of the cervix: early surgery (transvaginal) is recommended for cervicovaginal fibroids that are too large and cause difficulties in surgery; large fibroids that produce compression symptoms, pressing on the rectum, ureter or bladder; fibroids that grow rapidly and are suspected to be malignant; myomectomy is feasible for young patients who need to preserve their reproductive function, otherwise total hysterectomy is performed.  4.Ligamentous ligament myomectomy: suitable for those with large tumors or symptoms of compression; those with difficulty in differentiating between ligamentous ligamentous leiomyoma and solid ovarian tumors; those with rapid growth of leiomyoma, especially those suspected of malignant change.  5.Submucosal leiomyoma often leads to excessive menstrual flow and prolonged menstrual period, all of which need surgery. According to the site of the fibroid or the thickness of the tumor, the clamp method, collar method, peritomy method, electric cutting, torsional removal method, etc. can also be operated under the hysteroscope, until open, negative or laparoscopic hysterectomy.  6, laparoscopic or laparoscopic-assisted uterine fibroid surgery: myomectomy is mainly suitable for symptomatic fibroids, single or multiple subplasma fibroids with a maximum diameter of ≤10cm, and leiomyosarcoma with tissues are most suitable; single or multiple interstitial myomas with a minimum diameter of ≥4cm and a maximum diameter of ≤10cm; multiple myomas ≤10; the possibility of myoma malignancy has been excluded before surgery. The indications for laparoscopic assisted myomectomy can be relaxed appropriately. Laparoscopic or laparoscopic-assisted hysterectomy is mainly suitable for those with large fibroids, obvious symptoms, ineffective drug treatment, and no need to preserve reproductive function. However, those with tumors too large, heavy pelvic adhesions, suspected malignant tumors in the reproductive tract and general contraindications to laparoscopic surgery are not suitable.  7.Hysteroscopic surgery: symptomatic submucosal myoma and interstitial myoma protruding into the uterine cavity should be considered for hysteroscopic surgery first.