After a venous thrombosis in the arm, there is usually significant edema in the arm as well as pain, which is especially aggravated after exercise, but also significant pain when not exercising, because the thrombus produces stimulates an inflammatory response, and various inflammatory cells and inflammatory factors gather around the thrombus and blood vessels causing pain. If this pain is not relieved, non-steroidal anti-inflammatory drugs, such as aspirin or ibuprofen, can be used to control the local inflammatory response, thereby providing pain relief. If the pain is still severe, diuretics can also be used, and elevation of the affected limb to promote the return of fluid between the tissues to reduce swelling will also significantly relieve the pain.