Liver cancer is a malignant tumor occurring in the liver, including primary liver cancer and secondary liver cancer, and the commonly referred to liver cancer is primary liver cancer. Primary liver cancer is one of the most common malignant tumors in clinical practice. Primary liver cancer can be divided into hepatocellular liver cancer, cholangiocellular liver cancer and mixed liver cancer according to cellular typing. Hepatocellular hepatocellular carcinoma accounts for most of them and a few of them are hepatobiliary cell carcinoma, which are different in imaging and not difficult to distinguish clinically. Liver cancer is the third most common malignant tumor in China after gastric cancer and esophageal cancer, with a high mortality rate. Because its early symptoms are not obvious, it is already late when detected, which makes the chance of surgical resection greatly reduced. Symptoms in the late stage may include swelling and pain in the liver area, poor appetite, weakness, weight loss, jaundice, ascites and other symptoms. Currently, the clinical treatment measures include surgical resection, interventional therapy, radiofrequency ablation therapy, radiotherapy, combined Chinese and Western medicine treatment, etc. However, it must be emphasized that the treatment of liver cancer is comprehensive. For patients with advanced stage due to intrahepatic metastasis and distant metastasis (such as lung metastasis, bone metastasis, etc.), the current palliative treatment methods include cancer interventional chemoembolization, radiofrequency ablation of liver cancer and oral Chinese medicine (such as Sophora granules) anti-tumor treatment, which may slow down tumor growth and prolong patient’s survival, but there are still controversies. In conclusion, the treatment of liver cancer emphasizes early detection, early diagnosis and early treatment. For patients suffering from hepatitis B, hepatitis C and cirrhosis, they must pay attention, actively treat hepatitis and cirrhosis, and review regularly.